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CASE REPORT
Year : 2018  |  Volume : 22  |  Issue : 1  |  Page : 36-38

Anti-tumor necrosis factor-induced palmoplantar psoriasis: Case series


Department of Dermatology, College of Medicine, Al-Imam Muhammad Ibn Saud Islamic University, Riyadh, Saudi Arabia

Correspondence Address:
Dr. Saad Altalhab
Department of Dermatology, College of Medicine, Al-Imam Muhammad Ibn Saud Islamic University, P. O. Box: 5701, Riyadh 11432
Saudi Arabia
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jdds.jdds_6_18

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Palmoplantar pustular psoriasis (PPP) is a very uncommon form of psoriasis. Patients usually present with sterile, intraepidermal pustules over palms and soles, and it is difficult to treat. Women and smokers may be at a higher risk of getting PPP. Here, we report 2 patients who developed new PPP lesions after initiation of adalimumab (Humira®). Case reports are for a 19-year-old female diagnosed with Crohn's disease on February 2012 after a long history of abdominal pain and bleeding and a 34-year-old female who had psoriatic arthritis with no skin lesions since November 2012. Our recommendation is for the patients to be controlled with potent topical corticosteroids, keratolytics, Vitamin D analogs, phototherapy, increases in baseline methotrexate doses, and cyclosporine as needed.


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